
Name: | Amlodipine EP Impurity B |
Catalogue No. | VL19002 |
CAS No. | 721958-72-1 |
Molecular Formula | C29H32ClN3O7 |
Molecular Weight | 570.0 |
Status | In-stock |
IUPAC Name | 3-Ethyl 5-methyl 4-(2-chlorophenyl)-6-methyl-2-[[2- [[2-(methylcarbamoyl)benzoyl]amino]ethoxy]methyl]-1,4-dihydropyridine-3,5-dicarboxylate |
Synonyms | Amlodipine Related Compound B/Methylamino |
Appearance | Pale Yellow Powder |
Description | Amlodipine EP Impurity B (CAS No: 721958-72-1) or N-[2-[(Methylamino)carbonyl]benzoyl] Amlodipine is an impurity produced while the synthesis of Amlodipine besylate that is a drug which belongs to the group of calcium channel blockers employed in the treatment of hypertension. |
References | Ananchenko, Gennady, et al. “Amlodipine Besylate.” Profiles of Drug Substances, Excipients and Related Methodology, 2012, pp. 31–77,https://doi.org/10.1016/b978-0-12-397220-0.00002-7.Dongre, Vaijanath G., et al. “Simultaneous Determination of Metoprolol Succinate and Amlodipine Besylate in Pharmaceutical Dosage Form by HPLC.” Journal of Pharmaceutical and Biomedical Analysis, vol. 46, no. 3, Feb. 2008, pp. 583–86,https://doi.org/10.1016/j.jpba.2007.11.006. |