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Amlodipine EP Impurity B

Amlodipine EP Impurity B

Catalogue No.: VL19002
CAS No.: 721958-72-1

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Name: Amlodipine EP Impurity B
Catalogue No. VL19002
CAS No. 721958-72-1
Molecular Formula C29H32ClN3O7
Molecular Weight 570.0
Status In-stock
IUPAC Name 3-Ethyl 5-methyl 4-(2-chlorophenyl)-6-methyl-2-[[2- [[2-(methylcarbamoyl)benzoyl]amino]ethoxy]methyl]-1,4-dihydropyridine-3,5-dicarboxylate
Synonyms Amlodipine Related Compound B/Methylamino
Appearance Pale Yellow Powder
Description Amlodipine EP Impurity B (CAS No: 721958-72-1) or N-[2-[(Methylamino)carbonyl]benzoyl] Amlodipine is an impurity produced while the synthesis of Amlodipine besylate that is a drug which belongs to the group of calcium channel blockers employed in the treatment of hypertension.
References Ananchenko, Gennady, et al. “Amlodipine Besylate.” Profiles of Drug Substances, Excipients and Related Methodology, 2012, pp. 31–77,https://doi.org/10.1016/b978-0-12-397220-0.00002-7.Dongre, Vaijanath G., et al. “Simultaneous Determination of Metoprolol Succinate and Amlodipine Besylate in Pharmaceutical Dosage Form by HPLC.” Journal of Pharmaceutical and Biomedical Analysis, vol. 46, no. 3, Feb. 2008, pp. 583–86,https://doi.org/10.1016/j.jpba.2007.11.006.‌

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