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Anastrozole EP Impurity B

Anastrozole EP Impurity B

Catalogue No.: VL2490006
CAS No.: 1216898-82-6

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Name: Anastrozole EP Impurity B
Catalogue No. VL2490006
CAS No. 1216898-82-6
Molecular Formula C30H31N9
Molecular Weight 517.63
Status In-stock
IUPAC Name 2,3-Bis[3-(1-cyano-1-methylethyl)-5-(1H,1,2,4-triazole-1-ylmethyl)phenyl]-2-methylpropionitrile
Synonyms Anastrozole Dimer Impurity
Description Anastrozole EP Impurity B (CAS No: 1216898-82-6) or :2,3-Bis[3-(1-cyano-1-methylethyl)-5-(1H,1,2,4-triazole-1-ylmethyl)phenyl]-2-methylpropionitrile,Anastrozole EP Impurity B is an impurity of Anastrozole. it is used in the treatment of postmenopausal women with estrogen-responsive breast cancer by decreasing circulating estrogen levels
References Gangadhara, Sharath, and Gianfilippo Bertelli. “Long-Term Efficacy and Safety of Anastrozole for Adjuvant Treatment of Early Breast Cancer in Postmenopausal Women.” Therapeutics and Clinical Risk Management, vol. 5, 2009, pp. 291–300, www.ncbi.nlm.nih.gov/pmc/articles/PMC2690973/.

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