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Apixaban Inhouse Impurity J

Apixaban Inhouse Impurity J

Catalogue No.: VE008157
CAS No.: N/A

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Name: Apixaban Inhouse Impurity J
Catalogue No. VE008157
Molecular Formula C27H27ClN4O5
Molecular Weight 522.98 g/mol
Status In-Stock
IUPAC Name Ethyl 6-(4-(5-chloropentanamido)phenyl)-1-(4-methoxyphenyl)-7-oxo-6,7-dihydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
Synonyms Apixaban Impurity 16VE008157
Description Apixaban Inhouse Impurity J (CAS No: N/A) or Ethyl 6-(4-(5-chloropentanamido)phenyl)-1-(4-methoxyphenyl)-7-oxo-6,7-dihydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate is an impurity of apixaban, Inhibition of factor Xa leads to decreased conversion of factor II (prothrombin) to IIa, resulting in decreased thrombin generation.
References Hurst, Katherine, et al. “Quick Reference Guide to Apixaban.” Vascular Health and Risk Management, vol. Volume 13, July 2017, pp. 263–267, 10.2147/vhrm.s121944.

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