| Name: | Apixaban Inhouse Impurity J |
| Catalogue No. | VE008157 |
| CAS No. | N/A |
| Molecular Formula | C27H27ClN4O5 |
| Molecular Weight | 522.98 g/mol |
| Status | In-Stock |
| IUPAC Name | Ethyl 6-(4-(5-chloropentanamido)phenyl)-1-(4-methoxyphenyl)-7-oxo-6,7-dihydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate |
| Synonyms | Apixaban Impurity 16VE008157 |
| Description | Apixaban Inhouse Impurity J (CAS No: N/A) or Ethyl 6-(4-(5-chloropentanamido)phenyl)-1-(4-methoxyphenyl)-7-oxo-6,7-dihydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate is an impurity of apixaban, Inhibition of factor Xa leads to decreased conversion of factor II (prothrombin) to IIa, resulting in decreased thrombin generation. |
| References | Hurst, Katherine, et al. “Quick Reference Guide to Apixaban.” Vascular Health and Risk Management, vol. Volume 13, July 2017, pp. 263–267, 10.2147/vhrm.s121944. |
