
Name: | Apixaban O-Desmethyl Impurity |
Catalogue No. | VL3170009 |
CAS No. | 503612-76-8 |
Molecular Formula | C24H23N5O4 |
Molecular Weight | 445.48 |
Status | In-stock |
IUPAC Name | 4,5,6,7-Tetrahydro-1-(4-hydroxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide |
Description | Apixaban O-Desmethyl Impurity (CAS No: 503612-76-8) or 4,5,6,7-Tetrahydro-1-(4-hydroxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide is a selective factor Xa inhibitor by Inhibition of factor Xa leads to decreased conversion of factor II (prothrombin) to IIa, resulting in decreased thrombin generation used in help prevent strokes or blood clots. |
References | Hurst, Katherine, et al. “Quick Reference Guide to Apixaban.” Vascular Health and Risk Management, vol. Volume 13, July 2017, pp. 263–267, 10.2147/vhrm.s121944. |