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Apremilast Impurity 11

Apremilast Impurity 11

Catalogue No.: VE008021
CAS No.: 1384439-80-8

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Name: Apremilast Impurity 11
Catalogue No. VE008021
CAS No. 1384439-80-8
Molecular Formula C17H16N2O6S
Molecular Weight 376.38 g/mol
Status In-Stock
IUPAC Name 4-Amino-2-[(1S)-1-(3 ,4-dihydroxyphenyl)-2-(methylsulfonyl)ethyl]-1H-isoindole-1,3(2H)-dione
Synonyms Apremilast N-Desacetyl O4-Desmethyl O3-Desethyl Impurity
Description Apremilast Impurity 11 (CAS NO.-1384439-80-8) IUPAC Name-4-Amino-2-[(1S)-1-(3 ,4-dihydroxyphenyl)-2-(methylsulfonyl)ethyl]-1H-isoindole-1,3(2H)-dione. Apremilast is an oral phosphodiesterase 4 inhibitor that has an impact on a wide range of inflammatory mediators involved in psoriasis and psoriatic arthritis, this is the novel treatment that focuses on maintaining a balance between pro-inflammatory and anti-inflammatory signals.
References Schafer, Peter. “Apremilast Mechanism of Action and Application to Psoriasis and Psoriatic Arthritis.” Biochemical Pharmacology, vol. 83, no. 12, June 2012, pp. 1583–90, https://doi.org/10.1016/j.bcp.2012.01.001.

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