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Apremilast Impurity 12

Apremilast Impurity 12

Catalogue No.: VE008022
CAS No.: 1384440-16-7

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Name: Apremilast Impurity 12
Catalogue No. VE008022
CAS No. 1384440-16-7
Molecular Formula C19H20N2O6S
Molecular Weight 404.44 g/mol
Status In-Stock
IUPAC Name (S)-4-amino-2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)isoindoline-1,3-dione
Synonyms N-Desacetyl O4-Desmethyl Apremilast
Description Apremilast Impurity 12 (CAS NO.- 1384440-16-7) IUPAC Name-(S)-4-amino-2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)isoindoline-1,3-dione. Apremilast is an oral phosphodiesterase 4 inhibitor that has an impact on a wide range of inflammatory mediators involved in psoriasis and psoriatic arthritis, this is a novel treatment that focuses on maintaining a balance between pro-inflammatory and anti-inflammatory signals.
References Schafer, Peter. “Apremilast Mechanism of Action and Application to Psoriasis and Psoriatic Arthritis.” Biochemical Pharmacology, vol. 83, no. 12, June 2012, pp. 1583–90, https://doi.org/10.1016/j.bcp.2012.01.001.

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