| Name: | Apremilast Impurity 12 |
| Catalogue No. | VE008022 |
| CAS No. | 1384440-16-7 |
| Molecular Formula | C19H20N2O6S |
| Molecular Weight | 404.44 g/mol |
| Status | In-Stock |
| IUPAC Name | (S)-4-amino-2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)isoindoline-1,3-dione |
| Synonyms | N-Desacetyl O4-Desmethyl Apremilast |
| Description | Apremilast Impurity 12 (CAS NO.- 1384440-16-7) IUPAC Name-(S)-4-amino-2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)isoindoline-1,3-dione. Apremilast is an oral phosphodiesterase 4 inhibitor that has an impact on a wide range of inflammatory mediators involved in psoriasis and psoriatic arthritis, this is a novel treatment that focuses on maintaining a balance between pro-inflammatory and anti-inflammatory signals. |
| References | Schafer, Peter. “Apremilast Mechanism of Action and Application to Psoriasis and Psoriatic Arthritis.” Biochemical Pharmacology, vol. 83, no. 12, June 2012, pp. 1583–90, https://doi.org/10.1016/j.bcp.2012.01.001. |
