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Apremilast Impurity 6

Apremilast Impurity 6

Catalogue No.: VE008015
CAS No.: 1384967-20-7

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Name: Apremilast Impurity 6
Catalogue No. VE008015
CAS No. 1384967-20-7
Molecular Formula C20H20N2O7S
Molecular Weight 432.5 g/mol
Status In-Stock
IUPAC Name (S)-N-(2-(1-(3-hydroxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide
Synonyms Apremilast O-Desethyl
Description Apremilast Impurity 6 (CAS NO.-1384967-20-7) IUPAC Name-(S)-N-(2-(1-(3-hydroxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide. Apremilast is an oral phosphodiesterase 4 inhibitor that have an impact on a wide range of inflammatory mediators involved in psoriasis and psoriatic arthritis, this is the novel treatment that focuses on maintaining a balance between pro-inflammatory and anti-inflammatory signals.
References Schafer, Peter. “Apremilast Mechanism of Action and Application to Psoriasis and Psoriatic Arthritis.” Biochemical Pharmacology, vol. 83, no. 12, June 2012, pp. 1583–90, https://doi.org/10.1016/j.bcp.2012.01.001.

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