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Aprepitant Related Compound A

Aprepitant Related Compound A

Catalogue No.: VL1110001
CAS No.: 1148113-53-4

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Name: Aprepitant Related Compound A
Catalogue No. VL1110001
CAS No. 1148113-53-4
Molecular Formula C₂₃H₂₁F₇N₄O₃
Molecular Weight 534.43
Status In-stock
IUPAC Name 3-[[(2R,3R)-2-[(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluoro phenyl)morpholino]methyl]-1H-1,2,4-triazol-5(4H)-one
Synonyms Aprepitant EP Impurity E
Description Aprepitant Related Compound A (CAS No: 1148113-53-4) or Aprepitant EP Impurity E is an impurity of Aprepitant that is used for the prevention of acute and delayed chemotherapy-induced nausea and vomiting by acting on NK1 receptors and regulates emesis by binding with a peptide neurotransmitter.
References “SEPARATION and QUANTIFICATION of PROCESS RELATED IMPURITIES and DIASTEREOMERS in APREPITANT BULK DRUG SUBSTANCE.” Journal of Liquid Chromatography & Related Technologies, 2012, www.tandfonline.com/doi/abs/10.1080/10826076.2011.606586.

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