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Aprepitant Related Compound B

Aprepitant Related Compound B

Catalogue No.: VL1110002
CAS No.: 172822-29-6

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Name: Aprepitant Related Compound B
Catalogue No. VL1110002
CAS No. 172822-29-6
Molecular Formula C23H21F7N4O3
Molecular Weight 534.43
Status In-stock
IUPAC Name 3-[[(2R,3R)-2-[(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluoro phenyl)morpholino]methyl]-1H-1,2,4-triazol-5(4H)-one
Synonyms Aprepitant EP Impurity D
Description Aprepitant Related Compound B (CAS NO.-172822-29-6) IUPAC Name-3-[[(2R,3R)-2-[(R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluoro phenyl)morpholino]methyl]-1H-1,2,4-triazol-5(4H)-one. Aprepitant belongs to the neurokinin NK1 receptor antagonists class of agents. it is given in combination with other agents in order to prevent acute and delayed chemotherapy-induced nausea and vomiting (CINV) associated with highly emetogenic chemotherapy in adults. aprepitant (125mg day 1, 80mg days 2 and 3
References Dando, Toni M., and Caroline M. Perry. “Aprepitant.” Drugs, vol. 64, no. 7, 2004, pp. 777–94, https://doi.org/10.2165/00003495-200464070-00013. Curran, Monique P., and Dean M. Robinson. “Aprepitant.” Drugs, vol. 69, no. 13, Sept. 2009, pp. 1853–78, https://doi.org/10.2165/11203680-000000000-00000.

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