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Atorvastatin 2,3-Anhydro lactone

Atorvastatin 2,3-Anhydro lactone

Catalogue No.: VL10040
CAS No.: 442851-50-5

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Name: Atorvastatin 2,3-Anhydro lactone
Catalogue No. VL10040
CAS No. 442851-50-5
Molecular Formula C33H31FN2O3
Molecular Weight 522.61 g/mol
Status In-Stock
IUPAC Name 1-[2-[(2S)-3,6-Dihydro-6-oxo-2H-pyran-2-yl]ethyl]-5-(4-fluorophenyl)-2-(1-methylethyl)-N,4-diphenyl-1H-pyrrole-3-carboxamide
Synonyms 3-Dehydroxy 2,3-Dehydro Atorvastatin Lactone / Atorvastatin Dehydro Lactone /Atorvastatin Eliminated Lactone
Description Atorvastatin 2,3-Anhydro lactone or 3-Dehydroxy 2,3-Dehydro Atorvastatin Lactone or Atorvastatin Dehydro Lactone or Atorvastatin Eliminated Lactone (CAS No: 442851-50-5), it is highly protein-bound in serum to α-1-acid glycoprotein (AAG) and albumin, it is extensively metabolized in the liver, primarily by cytochrome (CYP450)3A isoenzymes – 3A4 and 3A5.
References McIver, Lindsey A., and Momin S. Siddique. “Atorvastatin.” Nih.gov, StatPearls Publishing, 5 Jan. 2019, www.ncbi.nlm.nih.gov/books/NBK430779/.

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