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Atorvastatin Amlodipine Dimer Or Adduct

Atorvastatin Amlodipine Dimer Or Adduct

Catalogue No.: VL10041
CAS No.: 425408-16-8

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Name: Atorvastatin Amlodipine Dimer Or Adduct
Catalogue No. VL10041
CAS No. 425408-16-8
Description Atorvastatin Amlodipine Dimer Or Adduct (CAS No: 425408-16-8) or 3-ethyl 5-methyl 4-(2-chlorophenyl)-2-((2-((3R,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanamido)ethoxy)methyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate is an impurity of atorvastatin. it is rapidly absorbed after oral administration with a peak plasma concentration at 1 to 2 hours and bioavailability is low at 14% due to extensive first-pass metabolism.
References McIver, Lindsey A., and Momin S. Siddique. “Atorvastatin.” Nih.gov, StatPearls Publishing, 5 Jan. 2019, www.ncbi.nlm.nih.gov/books/NBK430779/.

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