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Atorvastatin Epoxy Tetrahydrofuran Analog

Atorvastatin Epoxy Tetrahydrofuran Analog

Catalogue No.: VL10030
CAS No.: 873950-19-7

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Name: Atorvastatin Epoxy Tetrahydrofuran Analog
Catalogue No. VL10030
CAS No. 873950-19-7
Molecular Formula C₂₆H₂₄FNO₅
Molecular Weight 449.47
Status In-stock
IUPAC Name 4-(4-Fluorophenyl)-2,4-dihydroxy-2-isopropyl-N,5-diphenyl-3,6-dioxabicyclo[3.1.0]hexane-1-carboxamid
Synonyms Atorvastatin Epoxy Dihydroxy
Appearance White Solid
Description Atorvastatin epoxy tetrahydrofuran analog (CAS No: 873950-19-7) or 4-(4-Fluorophenyl)-2,4-dihydroxy-2-isopropyl-N,5-diphenyl-3,6-dioxabicyclo[3.1.0]hexane-1-carboxamide is an impurity of atorvastatin. it is used for the treatment of For patients with coronary heart disease, atorvastatin has approval as a therapy to reduce the risk of non-fatal myocardial infarction, fatal and non-fatal stroke, revascularization procedures, hospitalizations for congestive heart failure, and angina.
References McIver, Lindsey A., and Momin S. Siddique. “Atorvastatin.” Nih.gov, StatPearls Publishing, 5 Jan. 2019, www.ncbi.nlm.nih.gov/books/NBK430779/. Black, Donald M., et al. “An Overview of the Clinical Safety Profile of Atorvastatin (Lipitor), a New HMG-CoA Reductase Inhibitor.” Archives of Internal Medicine, vol. 158, no. 6, Mar. 1998, p. 577, https://doi.org/10.1001/archinte.158.6.577.

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