
Name: | Atovaquone EP Impurity C |
Catalogue No. | VL1370004 |
CAS No. | 1809464-27-4 |
Molecular Formula | C22H17ClO3 |
Molecular Weight | 364.82 |
Status | In-stock |
IUPAC Name | 2-4-(4-Chlorophenyl)cyclohex-3-enyl]3hydroxynaphthalene-1,4-dione |
Synonyms | Didehydro Atovaquone |
Appearance | Yellow solid |
Description | Atovaquone EP Impurity C (CAS No: 1809464-27-4) or Didehydro Atovaquone is an impurity of second-generation non-mutagenic antipneumocystic agent Atovaquone that is used for the treatment of prophylaxis of Pneumocystis carinii infection and plasmodium falciparum malaria. |
References | Urquhart, Michael W. J., et al. “Managing Emerging Mutagenicity Risks: Late Stage Mutagenic Impurity Control within the Atovaquone Second Generation Synthesis.” Regulatory Toxicology and Pharmacology, vol. 99, Nov. 2018, pp. 22–32, https://doi.org/10.1016/j.yrtph.2018.08.004. |