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Azelastine EP Impurity A

Azelastine EP Impurity A

Catalogue No.: VL1100001
CAS No.: 613-94-5

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Name: Azelastine EP Impurity A
Catalogue No. VL1100001
CAS No. 613-94-5
Molecular Formula C7H8N2O
Molecular Weight 136.15
Status In-stock
IUPAC Name Benzoic Acid Hydrazide
Synonyms Benzohydrazide / Benzoyldiazane
Appearance Light Beige Solid
Description Azelastine EP Impurity A or 4-Benzoic Hydrazide (CAS No: 613-94-5) can be utilized in the inhibition of Myeloperoxidase through the initial ejection of the heme catalytic moiety. Myeloperoxidase catalyzes the breakdown of hydrogen peroxide and the formation of the potent oxidant hypochlorous acid.
References Huang, Jiansheng, et al. “Ordered Cleavage of Myeloperoxidase Ester Bonds Releases Active Site Heme Leading to Inactivation of Myeloperoxidase by Benzoic Acid Hydrazide Analogs.” Archives of Biochemistry and Biophysics, vol. 548, Apr. 2014, pp. 74–85, https://doi.org/10.1016/j.abb.2014.02.014.

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