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Bortezomib Related Compound B

Bortezomib Related Compound B

Catalogue No.: VL1200001
CAS No.: 289472-80-6

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Name: Bortezomib Related Compound B
Catalogue No. VL1200001
CAS No. 289472-80-6
Molecular Formula C14H14N4O2
Molecular Weight 270.29
Status In-stock
IUPAC Name 2S)-3-Phenyl-2-[(pyrazin-2-ylcarbonyl)amino]propanamide
Synonyms Bortezomib Impurity A / Bortezomib Amide Analog
Description Bortezomib Related Compound B (CAS No: 289472-80-6) or 2S)-3-Phenyl-2-[(pyrazin-2-ylcarbonyl)amino]propanamide is associate impurity of Bortezomib.Bortezomib could be a proteasome inhibitor that not only targets the myeloma cell, but also acts within the bone marrow micro-environment, inhibiting the binding of myeloma cells to bone marrow stromal cells, as well as demonstrating anabolic effects on bone.
References “Sci-Hub | Development of Peptidomimetic Boronates as Proteasome Inhibitors | 10.1016/J.ejmech.2013.03.032.” Hkvisa.net, 2013, sci-hub.hkvisa.net/10.1016/j.ejmech.2013.03.032.

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