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Bosentan O-Desmethyl Impurity

Bosentan O-Desmethyl Impurity

Catalogue No.: VE007404
CAS No.: 253688-61-8

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Name: Bosentan O-Desmethyl Impurity
Catalogue No. VE007404
CAS No. 253688-61-8
Molecular Formula C26H27N5O6S
Molecular Weight 537.59 g/mol
Status In-Stock
IUPAC Name 4-(1,1-Dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-hydroxyphenoxy)[2,2’-bipyrimidin]-4-yl]benzenesulfonamide
Description Bosentan O-Desmethyl Impurity (CAS No: 253688-61-8) or 4-(1,1-Dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-hydroxyphenoxy)[2,2’-bipyrimidin]-4-yl]benzenesulfonamide is associate impurity of Bosentan. Bosentan is associate endothelin receptor antagonist utilized in the therapy of pulmonary arterial hypertension (PAH).
References Gabbay, Eli, et al. “Review of Bosentan in the Management of Pulmonary Arterial Hypertension.” Vascular Health and Risk Management, vol. 3, no. 6, Dove Medical Press, 2007, pp. 887–900, www.ncbi.nlm.nih.gov/pmc/articles/PMC2350123/.

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