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Canagliflozin Ring opening impurity

Canagliflozin Ring opening impurity

Catalogue No.: VE007523
CAS No.: N/A

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Name: Canagliflozin Ring opening impurity
Catalogue No. VE007523
Molecular Formula C24H27FO6S
Molecular Weight 462.53 g/mol
Status In-Stock
IUPAC Name (2S,3R,4R,5R)-1-(3-((5-(4-fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)hexane-1,2,3,4,5,6-hexaol
Description Canagliflozin Ring opening impurity (CAS No: N/A) Or (2S,3R,4R,5R)-1-(3-((5-(4-fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)hexane-1,2,3,4,5,6-hexaol, ring-opening product isomer degraded produces under high temperature,Canagliflozin inhibiting the transporter protein SGLT2 in the kidneys, which reduces renal glucose reabsorption.
References Sci-Hub | Carbohydrate malabsorption mechanism for tumor formation in rats treated with the SGLT2 inhibitor canagliflozin | 10.1016/j.cbi.2014.08.001. (2014). Retrieved December 31, 2021, from Sci-hub.ee website: https://sci-hub.ee/10.1016/j.cbi.2014.08.001

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