| Name: | Candesartan Cilexetil EP Impurity A |
| Catalogue No. | VL290022 |
| CAS No. | 139481-58-6 |
| Molecular Formula | C₂₆H₂₄N₆O₃ |
| Molecular Weight | 468.51 |
| Status | In-stock |
| IUPAC Name | 2-Ethoxy-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic Acid Et |
| Synonyms | Candesartan Ethyl Ester / Candesartan Cilexetil Related Compound A |
| Appearance | White powder |
| Description | Candesartan Cilexetil EP Impurity A (CAS No: 139481-58-6) or Candesartan Cilexetil / Candesartan Ethyl Ester / Candesartan Related Compound A is an impurity during the synthesis of sartans. Sartans are applied in several heart diseases such as heart failure, prevention of atrial fibrillation in heart failure, myocarditis, hypertension with vascular hypertrophy, etc. Sartans with other antihypertensive drugs is more effective due to their synergistic effect. |
| References | Tsvetkova, Dobrina, et al. “Quality Control of Impurities and Comparison of Pharmacokinetic Parameters of Angiotensin Receptor Antagonists.” Journal of Multidisciplinary Engineering Science Studies (JMESS), vol. 2, no. 7, 2016, pp. 2458–925, www.jmess.org/wp-content/uploads/2016/07/JMESSP13420141.pdf. |
