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Candesartan Cilexetil EP Impurity A

Candesartan Cilexetil EP Impurity A

Catalogue No.: VL290022
CAS No.: 139481-58-6

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Name: Candesartan Cilexetil EP Impurity A
Catalogue No. VL290022
CAS No. 139481-58-6
Molecular Formula C₂₆H₂₄N₆O₃
Molecular Weight 468.51
Status In-stock
IUPAC Name 2-Ethoxy-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic Acid Et
Synonyms Candesartan Ethyl Ester / Candesartan Cilexetil Related Compound A
Appearance White powder
Description Candesartan Cilexetil EP Impurity A (CAS No: 139481-58-6) or Candesartan Cilexetil / Candesartan Ethyl Ester / Candesartan Related Compound A is an impurity during the synthesis of sartans. Sartans are applied in several heart diseases such as heart failure, prevention of atrial fibrillation in heart failure, myocarditis, hypertension with vascular hypertrophy, etc. Sartans with other antihypertensive drugs is more effective due to their synergistic effect.
References Tsvetkova, Dobrina, et al. “Quality Control of Impurities and Comparison of Pharmacokinetic Parameters of Angiotensin Receptor Antagonists.” Journal of Multidisciplinary Engineering Science Studies (JMESS), vol. 2, no. 7, 2016, pp. 2458–925, www.jmess.org/wp-content/uploads/2016/07/JMESSP13420141.pdf.

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