
Name: | Candesartan Cilexetil EP Impurity G |
Catalogue No. | VL290020 |
CAS No. | 139481-59-7 |
Molecular Formula | C24H20N6O3 |
Molecular Weight | 440.45 |
Status | In-stock |
IUPAC Name | (1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-2-ethoxybenzimidazole-7-carboxylic acid) |
Synonyms | Candesartan Related Compound G |
Appearance | White Powder |
Description | Candesartan Cilexetil EP Impurity G or Candesartan Related Compound G (CAS No.: 139481-59-7) is found as an impurity in the production of Candesartan Cilexetil. Candesartan cilexetil is a prodrug, hydrolyzed to candesartan during absorption from the gastrointestinal tract.. candesartan shows activities associated with vasopeptidase inhibitor omapatrilat and angiotensin II type 1 receptor blocker. |
References | Sudhakar Babu, K., et al. “A Validated Ultra High-Pressure Liquid Chromatography Method for Separation of Candesartan Cilexetil Impurities and Its Degradents in Drug Product.” Pharmaceutical Methods, vol. 3, no. 1, Jan. 2012, pp. 31–39, https://doi.org/10.4103/2229-4708.97718. |