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Candesartan Cilexetil EP Impurity G

Candesartan Cilexetil EP Impurity G

Catalogue No.: VL290020
CAS No.: 139481-59-7

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Name: Candesartan Cilexetil EP Impurity G
Catalogue No. VL290020
CAS No. 139481-59-7
Molecular Formula C24H20N6O3
Molecular Weight 440.45
Status In-stock
IUPAC Name (1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-2-ethoxybenzimidazole-7-carboxylic acid)
Synonyms Candesartan Related Compound G
Appearance White Powder
Description Candesartan Cilexetil EP Impurity G or Candesartan Related Compound G (CAS No.: 139481-59-7) is found as an impurity in the production of Candesartan Cilexetil. Candesartan cilexetil is a prodrug, hydrolyzed to candesartan during absorption from the gastrointestinal tract.. candesartan shows activities associated with vasopeptidase inhibitor omapatrilat and angiotensin II type 1 receptor blocker.
References Sudhakar Babu, K., et al. “A Validated Ultra High-Pressure Liquid Chromatography Method for Separation of Candesartan Cilexetil Impurities and Its Degradents in Drug Product.” Pharmaceutical Methods, vol. 3, no. 1, Jan. 2012, pp. 31–39, https://doi.org/10.4103/2229-4708.97718.

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