Cetirizine 4-chloro benzophenone impurity

Cetirizine 4-chloro benzophenone impurity

Catalogue No.: VL330011
CAS No.: 134-85-0

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Name: Cetirizine 4-chloro benzophenone impurity
Catalogue No. VL330011
CAS No. 134-85-0
Molecular Formula C₁₃H₉ClO
Molecular Weight 216.66
Status In-stock
IUPAC Name (4-Chlorophenyl)phenylmethanone
Synonyms Hydroxyzine 4-Chlorobenzophenone/ Meclizine EP Impurity C/ Levocloperastine CBP Intermediate
Description 4 chlorobenzophenone (CAS No: 134-85-0) or p-chlorobenzophenone is stereoselectively reduced to form (S)-p-chlorodiphenylmethanol. It is also used in the manufacturing of S-chlorphenoxamine (Systral) which is used as an anti-Parkinsonism agent.
References Christov, P., et al. “Effect of Matrix on (S)-p-Chlorodiphenylmethanol Production by Immobilized Debaryomyces Marama.” Process Biochemistry, vol. 34, no. 3, Apr. 1999, pp. 231–37, https://doi.org/10.1016/s0032-9592(98)00088-0. ‌Tambe, Amruta S., et al. “Gas Chromatographic Method for the Determination of Chlorobenzophenone Isomers.” Journal of Chromatography A, vol. 628, no. 1, Jan. 1993, pp. 143–47, https://doi.org/10.1016/0021-9673(93)80342-6. ‌

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