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Chlordiazepoxide EP impurity B

Chlordiazepoxide EP impurity B

Catalogue No.: VL3650001
CAS No.: 5958-24-7

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Name: Chlordiazepoxide EP impurity B
Catalogue No. VL3650001
CAS No. 5958-24-7
Molecular Formula C₁₅H₁₀Cl₂N₂O
Molecular Weight 305.16
Status In-stock
IUPAC Name 2-(Chloromethyl)-6-chloro-4-phenylquinazoline 3-Oxide
Appearance In-stock
Description Chlordiazepoxide EP impurity B (CAS No: 5958-24-7) or 2-(Chloromethyl)-6-chloro-4-phenylquinazoline 3-Oxide is an impurity during the synthesis of Chlordiazepoxide. They find their principal use as antianxiety agents. Chlordiazepoxide has sedative, appetite-increasing, and low analgesic actions. It attaches to benzodiazepine receptors at the GABA-A ligand-gated chloride channel complex and increases GABA's inhibitory effects.
References Childress, Scott J., and M. I. Gluckman. “1,4-Benzodiazepines.” Journal of Pharmaceutical Sciences, vol. 53, no. 6, June 1964, pp. 577–90, https://doi.org/10.1002/jps.2600530602. Ahwazi HH, Abdijadid S. Chlordiazepoxide. In: StatPearls. StatPearls Publishing, Treasure Island (FL); 2020. PMID: 31613439.

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