| Name: | Chloroquine Related Compound E |
| Catalogue No. | VE005912 |
| CAS No. | 5428-61-5 |
| Molecular Formula | C18H26ClN3 |
| Molecular Weight | 319.88 |
| Status | In-Stock |
| IUPAC Name | N4-(5-chloroquinolin-4-yl)-N1,N1-diethylpentane-1,4-diamine oxalate |
| Description | Chloroquine Related Compound E (CAS No: 5428-61-5) or N4-(5-chloroquinolin-4-yl)-N1, N1-diethylpentane-1,4-diamine oxalate is a metabolite of Chloroquine. It depicts satisfactory activity as an anti-malarial drug. Chloroquine shows its antimalarial effects by preventing the polymerization of heme into hemozoin. Chloroquine forms a drug-hemozoin complex thereby preventing additional polymerization. |
| References | RAMAZANI A, and BORNA H. “IN SILICO ANALYSIS and DEVELOPMENT of ANTI- MALARIAL COMPOUNDS against DIHYDROOROTATE DEHYDROGENASE USING CHEMBIOINFORMATIC TOOLS.” International Journal of Pharma and Bio Sciences, vol. 2, no. 2, 2011, p. B-122 - B-131. Goel P, Gerriets V. Chloroquine. In: StatPearls. StatPearls Publishing, Treasure Island (FL); 2020. PMID: 31855356. |
