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Chloroquine Related Compound E

Chloroquine Related Compound E

Catalogue No.: VE005912
CAS No.: 5428-61-5

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Name: Chloroquine Related Compound E
Catalogue No. VE005912
CAS No. 5428-61-5
Molecular Formula C18H26ClN3
Molecular Weight 319.88
Status In-Stock
IUPAC Name N4-(5-chloroquinolin-4-yl)-N1,N1-diethylpentane-1,4-diamine oxalate
Description Chloroquine Related Compound E (CAS No: 5428-61-5) or N4-(5-chloroquinolin-4-yl)-N1, N1-diethylpentane-1,4-diamine oxalate is a metabolite of Chloroquine. It depicts satisfactory activity as an anti-malarial drug. Chloroquine shows its antimalarial effects by preventing the polymerization of heme into hemozoin. Chloroquine forms a drug-hemozoin complex thereby preventing additional polymerization.
References RAMAZANI A, and BORNA H. “IN SILICO ANALYSIS and DEVELOPMENT of ANTI- MALARIAL COMPOUNDS against DIHYDROOROTATE DEHYDROGENASE USING CHEMBIOINFORMATIC TOOLS.” International Journal of Pharma and Bio Sciences, vol. 2, no. 2, 2011, p. B-122 - B-131. Goel P, Gerriets V. Chloroquine. In: StatPearls. StatPearls Publishing, Treasure Island (FL); 2020. PMID: 31855356.

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