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Chlorpromazine EP Impurity C (HCl salt)

Chlorpromazine EP Impurity C (HCl salt)

Catalogue No.: VE008053
CAS No.: 53-60-1

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Name: Chlorpromazine EP Impurity C (HCl salt)
Catalogue No. VE008053
CAS No. 53-60-1
Molecular Formula C17H21ClN2S
Molecular Weight 320.88 g/mol
Status In-Stock
IUPAC Name N,N-Dimethyl-10H-phenothiazine-10-propanamine hydrochloride
Synonyms Promazine
Description Chlorpheniramine EP Impurity B (CAS No: 1202-34-2) or 2,2'-Iminodipyridine; 2,2'-Bipyridylamine; 2,2'-Iminodipyridine is an impurity of Chlorpheniramine. It is a metal-complexing agent and an effective iron-chelating agent. Chlorpheniramine (CP) is a H1 blocker and can cause bronchodilatation.
References Sgaragli G;Ninci R;Della Corte L;Valoti M;Nardini M;Andreoli V;Moneti G. “Promazine. A Major Plasma Metabolite of Chlorpromazine in a Population of Chronic Schizophrenics.” Drug Metabolism and Disposition: The Biological Fate of Chemicals, vol. 14, no. 2, Drug Metab Dispos, 2021, pubmed.ncbi.nlm.nih.gov/2870904/. ‌“Atypical Antipsychotics: Mechanism of Action | FOCUS.” FOCUS, 2020, focus.psychiatryonline.org/doi/full/10.1176/foc.2.1.48.

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