| Name: | Chlorpromazine EP Impurity C (HCl salt) |
| Catalogue No. | VE008053 |
| CAS No. | 53-60-1 |
| Molecular Formula | C17H21ClN2S |
| Molecular Weight | 320.88 g/mol |
| Status | In-Stock |
| IUPAC Name | N,N-Dimethyl-10H-phenothiazine-10-propanamine hydrochloride |
| Synonyms | Promazine |
| Description | Chlorpheniramine EP Impurity B (CAS No: 1202-34-2) or 2,2'-Iminodipyridine; 2,2'-Bipyridylamine; 2,2'-Iminodipyridine is an impurity of Chlorpheniramine. It is a metal-complexing agent and an effective iron-chelating agent. Chlorpheniramine (CP) is a H1 blocker and can cause bronchodilatation. |
| References | Sgaragli G;Ninci R;Della Corte L;Valoti M;Nardini M;Andreoli V;Moneti G. “Promazine. A Major Plasma Metabolite of Chlorpromazine in a Population of Chronic Schizophrenics.” Drug Metabolism and Disposition: The Biological Fate of Chemicals, vol. 14, no. 2, Drug Metab Dispos, 2021, pubmed.ncbi.nlm.nih.gov/2870904/. “Atypical Antipsychotics: Mechanism of Action | FOCUS.” FOCUS, 2020, focus.psychiatryonline.org/doi/full/10.1176/foc.2.1.48. |
