| Name: | Chlortalidone Impurity J |
| Catalogue No. | VL1090011 |
| CAS No. | 956-92-3 |
| Molecular Formula | C₁₄H₁₀ClNO₂ |
| Molecular Weight | 259.69 |
| Status | In-Stock |
| IUPAC Name | 3-(4-Chlorophenyl)-2,3-dihydro-3-hydroxy-1H-isoindol-1-one |
| Description | Chlortalidone Impurity J (CAS No: 956-92-3) or 3-(4-Chlorophenyl)-2,3-dihydro-3-hydroxy-1H-isoindol-1-one is an analog of Chlorthalidone that has potential hyperglycemic and antidiuretic activities. Chlorthalidone promotes mineral retention in patients with idiopathic hypercalciuria. Chlorthalidone has proven efficacy to reduce cardiovascular morbidity and mortality. |
| References | Wales, J. K., et al. “The Hyperglycemic and Antidiuretic Activity of a Phthalimidine Analogue: 1-Oxo-3-(4’-Chlorophenyl)-3-Hydroxyisoindoline (C3/76).” Experimental Biology and Medicine, vol. 128, no. 2, June 1968, pp. 581–87, https://doi.org/10.3181/00379727-128-33072. Coe, Fredric L., et al. “Chlorthalidone Promotes Mineral Retention in Patients with Idiopathic Hypercalciuria.” Kidney International, vol. 33, no. 6, June 1988, pp. 1140–46, https://doi.org/10.1038/ki.1988.122. Bakris, George L., |
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