| Name: | Chlortetracycline EP Impurity E |
| Catalogue No. | VE008304 |
| CAS No. | 14206-59-8 |
| Molecular Formula | C21H21ClN2O8 |
| Molecular Weight | 464.85 g/mol |
| Status | In-Stock |
| IUPAC Name | (4R,4aS,5aS,6S,12aS)-7-Chloro-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide |
| Synonyms | Demeclocycline EP Impurity B / 4-Epi Demeclocycline / 4-Epi Demethyl Chlortetracycline |
| Description | Chlortetracycline EP Impurity E (CAS No: 14206-59-8) or Demeclocycline EP Impurity B / 4-Epi Demeclocycline / 4-Epi Demethyl Chlortetracycline is an impurity of Chlortetracycline that is a Tetracycline analog as a gelatinase inhibitor. It is evaluated for the treatment of diseases such as rheumatoid arthritis and multiple sclerosis. |
| References | Paemen, Liesbet, et al. “The Gelatinase Inhibitory Activity of Tetracyclines and Chemically Modified Tetracycline Analogues as Measured by a Novel Microtiter Assay for Inhibitors.” Biochemical Pharmacology, vol. 52, no. 1, July 1996, pp. 105–11, https://doi.org/10.1016/0006-2952(96)00168-2. |
