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Chlortetracycline EP Impurity E

Chlortetracycline EP Impurity E

Catalogue No.: VE008304
CAS No.: 14206-59-8

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Name: Chlortetracycline EP Impurity E
Catalogue No. VE008304
CAS No. 14206-59-8
Molecular Formula C21H21ClN2O8
Molecular Weight 464.85 g/mol
Status In-Stock
IUPAC Name (4R,4aS,5aS,6S,12aS)-7-Chloro-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
Synonyms Demeclocycline EP Impurity B / 4-Epi Demeclocycline / 4-Epi Demethyl Chlortetracycline
Description Chlortetracycline EP Impurity E (CAS No: 14206-59-8) or Demeclocycline EP Impurity B / 4-Epi Demeclocycline / 4-Epi Demethyl Chlortetracycline is an impurity of Chlortetracycline that is a Tetracycline analog as a gelatinase inhibitor. It is evaluated for the treatment of diseases such as rheumatoid arthritis and multiple sclerosis.
References Paemen, Liesbet, et al. “The Gelatinase Inhibitory Activity of Tetracyclines and Chemically Modified Tetracycline Analogues as Measured by a Novel Microtiter Assay for Inhibitors.” Biochemical Pharmacology, vol. 52, no. 1, July 1996, pp. 105–11, https://doi.org/10.1016/0006-2952(96)00168-2.

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