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Chlorthalidone EP Impurity A

Chlorthalidone EP Impurity A

Catalogue No.: VL1090004
CAS No.: N/A

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Name: Chlorthalidone EP Impurity A
Catalogue No. VL1090004
CAS No. N/A
Molecular Formula C14H9ClO6S
Molecular Weight 340.74
Status In-stock
IUPAC Name 2-(4-Chloro-3-sulfobenzoyl)benzoic acid
Appearance White powder
Description Chlorthalidone EP Impurity A or 2-[3-(Aminosulfonyl)-4-chlorobenzoyl]-benzonic Acid is a potential metabolite of Chlorthalidone. Chlorthalidone has significantly reduced stroke and cardiovascular endpoints in several landmark trials. It is also a potent anti-diuretic and is frequently evaluated in hypertension.
References Salado, Salvador C., and Luz E. Vera-Avila. 'On-Line Solid-Phase Extraction and High-Performance Liquid Chromatographic Determination of Chlorthalidone in Urine.' Journal of Chromatography B: Biomedical Sciences and Applications, vol. 690, no. 1-2, Mar. 1997, pp. 195–202, https://doi.org/10.1016/s0378-4347(96)00396-9. ‌Ernst, Michael E., et al. 'Comparative Antihypertensive Effects of Hydrochlorothiazide and Chlorthalidone on Ambulatory and Office Blood Pressure.' Hypertension, vol. 47, no. 3,

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