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Chlorthalidone EP Impurity F

Chlorthalidone EP Impurity F

Catalogue No.: VL1090010
CAS No.: 1796929-84-4

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Name: Chlorthalidone EP Impurity F
Catalogue No. VL1090010
CAS No. 1796929-84-4
Molecular Formula C28H19Cl2N3O8S2
Molecular Weight 660.49
Status In-stock
IUPAC Name bis[2-Chloro-5-(1-hydroxy-3-oxo-2,3-dihydro-1H-isoindol-1-yl)benzenesulfonyl]amine
Appearance White Powder
Description Chlorthalidone EP Impurity F (CAS No: 1796929-84-4) or Chlorthalidone Dimer is a metabolite of Chlorthalidone. Chlorthalidone Dimer shows antidiuretic properties and is evaluated for hypertension. Chlorthalidone is evaluated for Systolic Hypertension in the Elderly Program (SHEP).
References Gad, Mohamed A., et al. “Strategies for Stabilizing Formulation and QbD Assisted Development of Robust Stability Indicating Method of Azilsartan Medoxomil/Chlorthalidone.” Journal of Pharmaceutical and Biomedical Analysis, vol. 178, Jan. 2020, p. 112910, https://doi.org/10.1016/j.jpba.2019.112910. ‌Hulley, Stephen B., et al. “Systolic Hypertension in the Elderly Program (SHEP): Antihypertensive Efficacy of Chlorthalidone.” The American Journal of Cardiology, vol. 56, no. 15, Dec. 1985, pp. 913–

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