| Name: | Cholecalciferol EP Impurity A |
| Catalogue No. | VE005880 |
| CAS No. | 22350-41-0 |
| Molecular Formula | C27H44O |
| Molecular Weight | 384.64 g/mol |
| Status | Under Development |
| IUPAC Name | (1S,3E)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(1R)-1,5-Dimethylhexyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylenecyclohexanol |
| Synonyms | 5,6-trans-Cholecalciferol |
| Description | Cholecalciferol EP Impurity A (CAS No: 22350-41-0) or 5,6-trans-Cholecalciferol is the major photoisomer of Vitamin D3. It is a biologically active analog of cholecalciferol (vitamin D). 5,6-trans-Cholecalciferol is studied for the biosynthesis of the Cholecalciferol-Dependent Calcium-Binding Protein in the Small Intestine of the Rachitic Chick. |
| References | Lawson, D. Eric M., and Phillip A. Bell. “Metabolism of Dihydrotachysterol and 5,6-Trans-Cholecalciferol in the Chick and the Rat.” Biochemical Journal, vol. 142, no. 1, July 1974, pp. 37–46, https://doi.org/10.1042/bj1420037. Tian, X. Q., et al. “Kinetic and Thermodynamic Studies of the Conversion of Previtamin D3 to Vitamin D3 in Human Skin.” Journal of Biological Chemistry, vol. 268, no. 20, July 1993, pp. 14888–92, https://doi.org/10.1016/s0021-9258(18)82416-4. Jones, L. T., et al. “The |