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Cimetidine EP Impurity A

Cimetidine EP Impurity A

Catalogue No.: VE006609
CAS No.: 52378-40-2

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Name: Cimetidine EP Impurity A
Catalogue No. VE006609
CAS No. 52378-40-2
Molecular Formula C10H15N5S2
Molecular Weight 269.39
Status In-stock
IUPAC Name Methyl 3-cyano-1-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl]ethyl] carbamimidothioate
Synonyms Cimetidine Methylsulfanyl Analog
Appearance Yellow Solid
Description Cimetidine EP Impurity A (CAS No: 52378-40-2) or Methyl 3-cyano-1-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl]ethyl] carbamimidothioate is a Methylsulfanyl Analog of Cimetidine. Cimetidine exerts its effects on acid-peptic disorders by blocking gastric acid secretion. The ability of cimetidine to block histamine stimulated acid secretion is due to its antagonistic effect at H2 receptors of parietal cells. Cimetidine inhibits the effects of gastrin and acetylcholine by interrupting the pathwa
References BROWN, T., et al. PURINES, PYRIMIDINES, and IMIDAZOLES. LIII: SYNTHESIS of SOME 5-HALOGENO-ANALOGUES of METIAMIDE and CIMETIDINE. 2021, p. -, pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=PASCAL8130207265. Koch-Weser, Jan, et al. “Cimetidine.” New England Journal of Medicine, vol. 299, no. 18, Nov. 1978, pp. 992–96, https://doi.org/10.1056/nejm197811022991806.

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