| Name: | Cimetidine EP Impurity A |
| Catalogue No. | VE006609 |
| CAS No. | 52378-40-2 |
| Molecular Formula | C10H15N5S2 |
| Molecular Weight | 269.39 |
| Status | In-stock |
| IUPAC Name | Methyl 3-cyano-1-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl]ethyl] carbamimidothioate |
| Synonyms | Cimetidine Methylsulfanyl Analog |
| Appearance | Yellow Solid |
| Description | Cimetidine EP Impurity A (CAS No: 52378-40-2) or Methyl 3-cyano-1-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl]ethyl] carbamimidothioate is a Methylsulfanyl Analog of Cimetidine. Cimetidine exerts its effects on acid-peptic disorders by blocking gastric acid secretion. The ability of cimetidine to block histamine stimulated acid secretion is due to its antagonistic effect at H2 receptors of parietal cells. Cimetidine inhibits the effects of gastrin and acetylcholine by interrupting the pathwa |
| References | BROWN, T., et al. PURINES, PYRIMIDINES, and IMIDAZOLES. LIII: SYNTHESIS of SOME 5-HALOGENO-ANALOGUES of METIAMIDE and CIMETIDINE. 2021, p. -, pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=PASCAL8130207265. Koch-Weser, Jan, et al. “Cimetidine.” New England Journal of Medicine, vol. 299, no. 18, Nov. 1978, pp. 992–96, https://doi.org/10.1056/nejm197811022991806. |
