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Cimetidine EP Impurity D (free base)

Cimetidine EP Impurity D (free base)

Catalogue No.: VE006611
CAS No.: 70172-53-1

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Name: Cimetidine EP Impurity D (free base)
Catalogue No. VE006611
CAS No. 70172-53-1
Molecular Formula C9H17N5S
Molecular Weight 227.3
Status In-stock
IUPAC Name 1-Methyl-3-[2-[[(5-methyl-1Himidazol-4-yl)methyl]sulfanyl]ethyl]guanidine
Synonyms Cimetidine Descyano Impurity
Appearance White Solid
Description Cimetidine EP Impurity D (free base) (CAS No: 70172-53-1) or Cimetidine Descyano Impurity is a major metabolite in the synthesis of Cimetidine. Complexes of Cimetidine Descyano are found to be less stable than those formed with cimetidine. Cimetidine has the ability to alter tumor cell adhesion, angiogenesis, and proliferation. It has an effect on the immune system and inhibition of postoperative immunosuppression.
References Lin, Qisui, et al. “Quantitation of Cimetidine and Cimetidine Sulfoxide in Serum by Solid-Phase Extraction and Solvent-Recycled Liquid Chromatography.” Journal of Analytical Toxicology, vol. 9, no. 4, July 1985, pp. 161–66, https://doi.org/10.1093/jat/9.4.161. Freijanes, Eduardo, and Guy Berthon. “Biological Significance of Cimetidine Sulfoxide Complexes with Copper(II) and Zinc(II) Ions during Cimetidine Treatment.” Inorganica Chimica Acta, vol. 124, no. 3, July 1986, pp. 141–47, https://doi.

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