| Name: | Cimetidine EP Impurity D (free base) |
| Catalogue No. | VE006611 |
| CAS No. | 70172-53-1 |
| Molecular Formula | C9H17N5S |
| Molecular Weight | 227.3 |
| Status | In-stock |
| IUPAC Name | 1-Methyl-3-[2-[[(5-methyl-1Himidazol-4-yl)methyl]sulfanyl]ethyl]guanidine |
| Synonyms | Cimetidine Descyano Impurity |
| Appearance | White Solid |
| Description | Cimetidine EP Impurity D (free base) (CAS No: 70172-53-1) or Cimetidine Descyano Impurity is a major metabolite in the synthesis of Cimetidine. Complexes of Cimetidine Descyano are found to be less stable than those formed with cimetidine. Cimetidine has the ability to alter tumor cell adhesion, angiogenesis, and proliferation. It has an effect on the immune system and inhibition of postoperative immunosuppression. |
| References | Lin, Qisui, et al. “Quantitation of Cimetidine and Cimetidine Sulfoxide in Serum by Solid-Phase Extraction and Solvent-Recycled Liquid Chromatography.” Journal of Analytical Toxicology, vol. 9, no. 4, July 1985, pp. 161–66, https://doi.org/10.1093/jat/9.4.161. Freijanes, Eduardo, and Guy Berthon. “Biological Significance of Cimetidine Sulfoxide Complexes with Copper(II) and Zinc(II) Ions during Cimetidine Treatment.” Inorganica Chimica Acta, vol. 124, no. 3, July 1986, pp. 141–47, https://doi. |
