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Cimetidine EP Impurity F

Cimetidine EP Impurity F

Catalogue No.: VL1900001
CAS No.: 55272-86-1

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Name: Cimetidine EP Impurity F
Catalogue No. VL1900001
CAS No. 55272-86-1
Molecular Formula C16H24N8S2
Molecular Weight 392.55
Status In-stock
IUPAC Name 2-Cyano-1,3-bis[2-[[(5-methyl-1H-imidazol-4-yl)methyl]-sulfanyl]ethyl] guanidine
Synonyms Cimetidine Bis Impurity
Appearance White Solid Powder
Description Cimetidine EP Impurity F (CAS No: 55272-86-1) or Cimetidine Bis Impurity is adulteration in Cimetidine. Cimetidine is an H2-receptor antagonist. It is known to elevate a variety of immunologic functions both in vivo and in vitro due to its inhibitory effects on suppressor-cell function. The ability of cimetidine to block histamine stimulated acid secretion is due to its antagonistic effect at H2 receptors of parietal cells.
References Ellis, D. R., et al. “Separation of Cimetidine and Related Materials by Aqueous and Non-Aqueous Capillary Electrophoresis.” Journal of Chromatography A, vol. 808, no. 1-2, May 1998, pp. 269–75, https://doi.org/10.1016/s0021-9673(98)00136-8. Kumar, Ashir. “Cimetidine: An Immunomodulator.” DICP, vol. 24, no. 3, Mar. 1990, pp. 289–95, https://doi.org/10.1177/106002809002400316. Koch-Weser, Jan, et al. “Cimetidine.” New England Journal of Medicine, vol. 299, no. 18, Nov. 1978, pp. 992–96, https:

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