| Name: | Cimetidine EP Impurity F |
| Catalogue No. | VL1900001 |
| CAS No. | 55272-86-1 |
| Molecular Formula | C16H24N8S2 |
| Molecular Weight | 392.55 |
| Status | In-stock |
| IUPAC Name | 2-Cyano-1,3-bis[2-[[(5-methyl-1H-imidazol-4-yl)methyl]-sulfanyl]ethyl] guanidine |
| Synonyms | Cimetidine Bis Impurity |
| Appearance | White Solid Powder |
| Description | Cimetidine EP Impurity F (CAS No: 55272-86-1) or Cimetidine Bis Impurity is adulteration in Cimetidine. Cimetidine is an H2-receptor antagonist. It is known to elevate a variety of immunologic functions both in vivo and in vitro due to its inhibitory effects on suppressor-cell function. The ability of cimetidine to block histamine stimulated acid secretion is due to its antagonistic effect at H2 receptors of parietal cells. |
| References | Ellis, D. R., et al. “Separation of Cimetidine and Related Materials by Aqueous and Non-Aqueous Capillary Electrophoresis.” Journal of Chromatography A, vol. 808, no. 1-2, May 1998, pp. 269–75, https://doi.org/10.1016/s0021-9673(98)00136-8. Kumar, Ashir. “Cimetidine: An Immunomodulator.” DICP, vol. 24, no. 3, Mar. 1990, pp. 289–95, https://doi.org/10.1177/106002809002400316. Koch-Weser, Jan, et al. “Cimetidine.” New England Journal of Medicine, vol. 299, no. 18, Nov. 1978, pp. 992–96, https: |
