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Cimetidine EP Impurity G

Cimetidine EP Impurity G

Catalogue No.: VE006613
CAS No.: 1609-06-9

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Name: Cimetidine EP Impurity G
Catalogue No. VE006613
CAS No. 1609-06-9
Molecular Formula C4H8N4
Molecular Weight 112.13
Status In-stock
IUPAC Name 2-Cyano-1,3-dimethylguanidine
Description Cimetidine EP Impurity G (CAS No: 1609-06-9) or 2-Cyano-1,3-dimethylguanidine is a nitrosoguanidine analog of Cimetidine. Cimetidine is a H2 receptor antagonist. It is commonly evaluated for gastric and duodenal ulcer disease. Cimetidine is known to have anticancer effects. Cimetidine has the ability to alter tumor cell adhesion, angiogenesis, and proliferation. It shows an effect on the immune system and inhibition of postoperative immunosuppression.
References Hansson, Lars O., et al. “Structural Determinants in Domain II of Human Glutathione Transferase M2-2 Govern the Characteristic Activities with Aminochrome, 2-Cyano-1, 3-Dimethyl-1-Nitrosoguanidine, and 1, 2-Dichloro-4-Nitrobenzene.” Protein Science, vol. 8, no. 12, Dec. 2008, pp. 2742–50, https://doi.org/10.1110/ps.8.12.2742. Kubecova, Martina, et al. “Cimetidine: An Anticancer Drug?” European Journal of Pharmaceutical Sciences, vol. 42, no. 5, Apr. 2011, pp. 439–44, https://doi.org/10.1016/j.e

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