
Name: | Cinacalcet 6 Formamide Impurity |
Catalogue No. | VL2310022 |
CAS No. | 650608-25-6 |
Molecular Formula | C13H13NO |
Molecular Weight | 199.25 |
Status | In-stock |
IUPAC Name | (R)-N-(1-(naphthalen-2-yl)ethyl)formamide |
Description | Cinacalcet 6 Formamide Impurity (CAS No: 650608-25-6) or (R)-N-(1-(naphthalen-2-yl)ethyl)formamide is a formamide impurity during the synthesis of Cinacalcet. Cinacalcet instantaneously normalizes serum calcium and diminishes intact parathyroid hormone (PTH) levels inside renal transplant patients with hypercalcaemia and persistent hyperparathyroidism. |
References | Vázquez, Santiago, et al. “Syntheses of Cinacalcet: An Enantiopure Active Pharmaceutical Ingredient (API).” Synthesis, vol. 48, no. 06, Jan. 2016, pp. 783–803, https://doi.org/10.1055/s-0035-1561506. Serra, A. L., et al. “Effective Control of Persistent Hyperparathyroidism with Cinacalcet in Renal Allograft Recipients.” Nephrology Dialysis Transplantation, vol. 22, no. 2, Sept. 2006, pp. 577–83, https://doi.org/10.1093/ndt/gfl560. |