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Cinacalcet 6 Formamide Impurity

Cinacalcet 6 Formamide Impurity

Catalogue No.: VL2310022
CAS No.: 650608-25-6

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Name: Cinacalcet 6 Formamide Impurity
Catalogue No. VL2310022
CAS No. 650608-25-6
Molecular Formula C13H13NO
Molecular Weight 199.25
Status In-stock
IUPAC Name (R)-N-(1-(naphthalen-2-yl)ethyl)formamide
Description Cinacalcet 6 Formamide Impurity (CAS No: 650608-25-6) or (R)-N-(1-(naphthalen-2-yl)ethyl)formamide is a formamide impurity during the synthesis of Cinacalcet. Cinacalcet instantaneously normalizes serum calcium and diminishes intact parathyroid hormone (PTH) levels inside renal transplant patients with hypercalcaemia and persistent hyperparathyroidism.
References Vázquez, Santiago, et al. “Syntheses of Cinacalcet: An Enantiopure Active Pharmaceutical Ingredient (API).” Synthesis, vol. 48, no. 06, Jan. 2016, pp. 783–803, https://doi.org/10.1055/s-0035-1561506. Serra, A. L., et al. “Effective Control of Persistent Hyperparathyroidism with Cinacalcet in Renal Allograft Recipients.” Nephrology Dialysis Transplantation, vol. 22, no. 2, Sept. 2006, pp. 577–83, https://doi.org/10.1093/ndt/gfl560.

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