| Name: | Cinacalcet 6-Ethanol Impurity |
| Catalogue No. | VL2310020 |
| CAS No. | 7228-47-9 |
| Molecular Formula | C12H12O |
| Molecular Weight | 172.22 |
| Status | In-Stock |
| IUPAC Name | 1-(Naphthalen-6-yl)Ethanol |
| Synonyms | Cinacalcet Impurity 4 |
| Description | Cinacalcet 6-Ethanol Impurity (CAS No: 7228-47-9) or Cinacalcet Impurity 4 is an impurity of Cinacalcet. Cinacalcet directly modulates the regulator of parathyroid hormone secretion, also known as the calcium-sensing receptor (CaR) in the parathyroid gland. Cinacalcet lowers the circulating PTH levels by elevating the sensitivity of the CaR to extracellular calcium. |
| References | Pasquini, Benedetta, et al. “Chiral Capillary Zone Electrophoresis in Enantioseparation and Analysis of Cinacalcet Impurities: Use of Quality by Design Principles in Method Development.” Journal of Chromatography A, vol. 1568, Sept. 2018, pp. 205–13, https://doi.org/10.1016/j.chroma.2018.07.021. Barman Balfour, Julia A., and Lesley J. Scott. “Cinacalcet Hydrochloride.” Drugs, vol. 65, no. 2, 2005, pp. 271–81, https://doi.org/10.2165/00003495-200565020-00007. |
