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Cinacalcet 6-Ethanol Impurity

Cinacalcet 6-Ethanol Impurity

Catalogue No.: VL2310020
CAS No.: 7228-47-9

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Name: Cinacalcet 6-Ethanol Impurity
Catalogue No. VL2310020
CAS No. 7228-47-9
Molecular Formula C12H12O
Molecular Weight 172.22
Status In-Stock
IUPAC Name 1-(Naphthalen-6-yl)Ethanol
Synonyms Cinacalcet Impurity 4
Description Cinacalcet 6-Ethanol Impurity (CAS No: 7228-47-9) or Cinacalcet Impurity 4 is an impurity of Cinacalcet. Cinacalcet directly modulates the regulator of parathyroid hormone secretion, also known as the calcium-sensing receptor (CaR) in the parathyroid gland. Cinacalcet lowers the circulating PTH levels by elevating the sensitivity of the CaR to extracellular calcium.
References Pasquini, Benedetta, et al. “Chiral Capillary Zone Electrophoresis in Enantioseparation and Analysis of Cinacalcet Impurities: Use of Quality by Design Principles in Method Development.” Journal of Chromatography A, vol. 1568, Sept. 2018, pp. 205–13, https://doi.org/10.1016/j.chroma.2018.07.021. Barman Balfour, Julia A., and Lesley J. Scott. “Cinacalcet Hydrochloride.” Drugs, vol. 65, no. 2, 2005, pp. 271–81, https://doi.org/10.2165/00003495-200565020-00007.

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