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Cinacalcet Impurity 27

Cinacalcet Impurity 27

Catalogue No.: VL2310045
CAS No.: 10420-89-0

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Name: Cinacalcet Impurity 27
Catalogue No. VL2310045
CAS No. 10420-89-0
Molecular Formula C12H13N
Molecular Weight 171.24
Status In-stock
IUPAC Name (S)-1-(naphthalen-1-yl)ethan-1-amine
Description Cinacalcet Impurity 27 or (S)-1-(naphthalen-1-yl)ethan-1-amine is an impurity found during the synthesis of Cinacalcet hydrochloride. Cinacalcet hydrochloride is the first agent of a new therapeutic class of calcimimetic compounds, which act by increasing the sensitivity of calcium-sensing receptors to the extracellular calcium ions, thus lowering the release of parathyroid hormone.
References Pasquini, Benedetta, et al. “Chiral Capillary Zone Electrophoresis in Enantioseparation and Analysis of Cinacalcet Impurities: Use of Quality by Design Principles in Method Development.” Journal of Chromatography A, vol. 1568, Sept. 2018, pp. 205–13, https://doi.org/10.1016/j.chroma.2018.07.021. ‌

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