| Name: | Cinacalcet Impurity 27 |
| Catalogue No. | VL2310045 |
| CAS No. | 10420-89-0 |
| Molecular Formula | C12H13N |
| Molecular Weight | 171.24 |
| Status | In-stock |
| IUPAC Name | (S)-1-(naphthalen-1-yl)ethan-1-amine |
| Description | Cinacalcet Impurity 27 or (S)-1-(naphthalen-1-yl)ethan-1-amine is an impurity found during the synthesis of Cinacalcet hydrochloride. Cinacalcet hydrochloride is the first agent of a new therapeutic class of calcimimetic compounds, which act by increasing the sensitivity of calcium-sensing receptors to the extracellular calcium ions, thus lowering the release of parathyroid hormone. |
| References | Pasquini, Benedetta, et al. “Chiral Capillary Zone Electrophoresis in Enantioseparation and Analysis of Cinacalcet Impurities: Use of Quality by Design Principles in Method Development.” Journal of Chromatography A, vol. 1568, Sept. 2018, pp. 205–13, https://doi.org/10.1016/j.chroma.2018.07.021. |
