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Cinacalcet Impurity C

Cinacalcet Impurity C

Catalogue No.: VL231009
CAS No.: 955373-56-5

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Name: Cinacalcet Impurity C
Catalogue No. VL231009
CAS No. 955373-56-5
Molecular Formula C22H20F3N
Molecular Weight 355.4
Status In-stock
IUPAC Name (R,E)-N-(1-(Naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl) phenyl)prop-2-en-1-amine
Appearance Off white solid
Description Cinacalcet Impurity C (CAS No: 955373-56-5) or (R,E)-N-(1-(Naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl) phenyl)prop-2-en-1-amine is a process adulteration of Cinacalcet. Cinacalcet is a calcium-sensing receptor allosteric activator that is beneficial in correcting signaling limitations caused because of AP2S1 mutations and also in ameliorating symptomatic hypercalcemia.
References Chaudhari, Yogesh J., et al. “Development and Validation of Stability Indicative Analysis for Cinacalcet Hydrochloride and Stress Study.” Journal of Scientific Research, vol. 65, no. 03, 2021, pp. 220–28, https://doi.org/10.37398/jsr.2021.650326. ‌Howles, Sarah A., et al. “Cinacalcet for Symptomatic Hypercalcemia Caused by AP2S1 Mutations.” New England Journal of Medicine, vol. 374, no. 14, Apr. 2016, pp. 1396–98, https://doi.org/10.1056/nejmc1511646.

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