| Name: | Cinacalcet Impurity C |
| Catalogue No. | VL231009 |
| CAS No. | 955373-56-5 |
| Molecular Formula | C22H20F3N |
| Molecular Weight | 355.4 |
| Status | In-stock |
| IUPAC Name | (R,E)-N-(1-(Naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl) phenyl)prop-2-en-1-amine |
| Appearance | Off white solid |
| Description | Cinacalcet Impurity C (CAS No: 955373-56-5) or (R,E)-N-(1-(Naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl) phenyl)prop-2-en-1-amine is a process adulteration of Cinacalcet. Cinacalcet is a calcium-sensing receptor allosteric activator that is beneficial in correcting signaling limitations caused because of AP2S1 mutations and also in ameliorating symptomatic hypercalcemia. |
| References | Chaudhari, Yogesh J., et al. “Development and Validation of Stability Indicative Analysis for Cinacalcet Hydrochloride and Stress Study.” Journal of Scientific Research, vol. 65, no. 03, 2021, pp. 220–28, https://doi.org/10.37398/jsr.2021.650326. Howles, Sarah A., et al. “Cinacalcet for Symptomatic Hypercalcemia Caused by AP2S1 Mutations.” New England Journal of Medicine, vol. 374, no. 14, Apr. 2016, pp. 1396–98, https://doi.org/10.1056/nejmc1511646. |
