| Name: | Cinnarizine EP Impurity B |
| Catalogue No. | VL195003 |
| CAS No. | 750512-44-8 |
| Molecular Formula | C26H28N2 |
| Molecular Weight | 368.51 |
| Status | In-stock |
| IUPAC Name | 1-(Diphenylmethyl)-4-[(2Z)-3-phenyl-2-propen-1-yl]piperazine; |
| Synonyms | cis-Cinnarizin |
| Appearance | White solid |
| Description | Cinnarizine EP Impurity B (CAS No: 750512-44-8) or 1-(Diphenylmethyl)-4-[(2Z)-3-phenyl-2-propen-1-yl]piperazine is a Z-isomer of Cinnarizine. Cinnarizine is a non-competitive antagonist of histamine, noradrenaline, nicotine, and angiotensin and has direct actions, all involve antagonism of the stimulated influx of extracellular calcium (Ca(Ca++) ions. |
| References | Shakhmaev, R. N., et al. “Iron-Catalyzed Synthesis of Cinnarizine.” Russian Journal of Organic Chemistry, vol. 51, no. 1, Jan. 2015, pp. 95–97, https://doi.org/10.1134/s1070428015010169. Towse, G. “Cinnarizine—a Labyrinthine Sedative.” The Journal of Laryngology & Otology, vol. 94, no. 9, Sept. 1980, pp. 1009–15, https://doi.org/10.1017/s0022215100089787. |
