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Cinnarizine EP Impurity C

Cinnarizine EP Impurity C

Catalogue No.: VL195004
CAS No.: 95062-18-3

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Name: Cinnarizine EP Impurity C
Catalogue No. VL195004
CAS No. 95062-18-3
Molecular Formula C35H35F2N2.Cl
Molecular Weight 557.11
Status In-stock
IUPAC Name (4-(Diphenylmethyl)-1,1-bis[(E)-3-phenylprop-2-enyl]piperazinium chloride;
Description Cinnarizine EP Impurity C (CAS No: 95062-18-3) or (4-(Diphenylmethyl)-1,1-bis[(E)-3-phenylprop-2-enyl]piperazinium chloride is an adulteration of Cinnarizine. Cinnarizine is a selective calcium blocker that has been used to treat and prevent vertigo. Cinnarizine is a potentially risky drug known to induce extrapyramidal reactions and depression.
References Haress, Nadia G. “Cinnarizine.” Profiles of Drug Substances, Excipients and Related Methodology, 2015, pp. 1–41, https://doi.org/10.1016/bs.podrm.2015.01.001. ‌Micheli, F., et al. “Flunarizine- and Cinnarizine-Induced Extrapyramidal Reactions.” Neurology, vol. 37, no. 5, May 1987, pp. 881–81, https://doi.org/10.1212/wnl.37.5.881.

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