| Name: | Cinnarizine EP Impurity D |
| Catalogue No. | VL195005 |
| CAS No. | 1199751-98-8 |
| Molecular Formula | C35H36N2 |
| Molecular Weight | 484.67 |
| Status | In-stock |
| IUPAC Name | 1-(Diphenylmethyl)-4-[(1RS,3E)-4-phenyl-1-[(E)-2-phenylethenyl]but-3-enyl]piperazine ; |
| Appearance | White solid |
| Description | Cinnarizine EP Impurity D (CAS No: 1199751-98-8) or 1-(Diphenylmethyl)-4-[4-phenyl-1-(2-phenylethenyl)-3-buten-1-yl]piperazine is an impure product of Cinnarizine. Cinnarizine is derived from piperazine and has antihistaminic, sedative, and calcium-channel blocking activity. It is evaluated for the symptomatic relief of nausea, vertigo, treatment of motion sickness, and cerebral vascular disorders. |
| References | Haress, Nadia G. “Cinnarizine.” Profiles of Drug Substances, Excipients and Related Methodology, 2015, pp. 1–41, https://doi.org/10.1016/bs.podrm.2015.01.001. Ahmed, Amal B., et al. “Simultaneous Determination of Dimenhydrinate, Cinnarizine and Cinnarizine Impurity by TLC and HPLC Chromatographic Methods.” Bulletin of Faculty of Pharmacy, Cairo University, vol. 55, no. 1, June 2017, pp. 163–69, https://doi.org/10.1016/j.bfopcu.2017.01.003 |
