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Cinnarizine EP Impurity D

Cinnarizine EP Impurity D

Catalogue No.: VL195005
CAS No.: 1199751-98-8

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Name: Cinnarizine EP Impurity D
Catalogue No. VL195005
CAS No. 1199751-98-8
Molecular Formula C35H36N2
Molecular Weight 484.67
Status In-stock
IUPAC Name 1-(Diphenylmethyl)-4-[(1RS,3E)-4-phenyl-1-[(E)-2-phenylethenyl]but-3-enyl]piperazine ;
Appearance White solid
Description Cinnarizine EP Impurity D (CAS No: 1199751-98-8) or 1-(Diphenylmethyl)-4-[4-phenyl-1-(2-phenylethenyl)-3-buten-1-yl]piperazine is an impure product of Cinnarizine. Cinnarizine is derived from piperazine and has antihistaminic, sedative, and calcium-channel blocking activity. It is evaluated for the symptomatic relief of nausea, vertigo, treatment of motion sickness, and cerebral vascular disorders.
References Haress, Nadia G. “Cinnarizine.” Profiles of Drug Substances, Excipients and Related Methodology, 2015, pp. 1–41, https://doi.org/10.1016/bs.podrm.2015.01.001. ‌Ahmed, Amal B., et al. “Simultaneous Determination of Dimenhydrinate, Cinnarizine and Cinnarizine Impurity by TLC and HPLC Chromatographic Methods.” Bulletin of Faculty of Pharmacy, Cairo University, vol. 55, no. 1, June 2017, pp. 163–69, https://doi.org/10.1016/j.bfopcu.2017.01.003

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