| Name: | Citalopram EP Impurity D (HCl salt) |
| Catalogue No. | VE008105 |
| CAS No. | 97743-99-2 |
| Molecular Formula | C19H20ClFN2O |
| Molecular Weight | 346.83 g/mol |
| Status | In-Stock |
| IUPAC Name | 1-(4'-Fluorophenyl)-1-(3-(methylamino)propyl)-1,3-dihydro isobenzo furan-5-carbonitrile hydrochloride |
| Synonyms | EsCitalopram EP Impurity D/ Citalopram Related Compound D/ N-Desmethyl Citalopram |
| Description | Citalopram EP Impurity D (HCl salt) (CAS No: 97743-99-2) or Citalopram Related Compound D/ N-Desmethyl Citalopram is a major metabolite of Citalopram. Citalopram is a selective 5-hydroxytryptamine reuptake inhibitor that has been used primarily in the treatment of major depression. Citalopram had efficacy similar to tricyclic or tetracyclic antidepressants. |
| References | Velez de Mendizabal, Nieves, et al. “A Population PK Model for Citalopram and Its Major Metabolite, N-Desmethyl Citalopram, in Rats.” Journal of Pharmacokinetics and Pharmacodynamics, vol. 42, no. 6, Sept. 2015, pp. 721–33, https://doi.org/10.1007/s10928-015-9448-7. Noble, Stuart, and Paul Benfield. “Citalopram.” CNS Drugs, vol. 8, no. 5, Nov. 1997, pp. 410–31, https://doi.org/10.2165/00023210-199708050-00009. |
