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Citalopram EP Impurity D (HCl salt)

Citalopram EP Impurity D (HCl salt)

Catalogue No.: VE008105
CAS No.: 97743-99-2

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Name: Citalopram EP Impurity D (HCl salt)
Catalogue No. VE008105
CAS No. 97743-99-2
Molecular Formula C19H20ClFN2O
Molecular Weight 346.83 g/mol
Status In-Stock
IUPAC Name 1-(4'-Fluorophenyl)-1-(3-(methylamino)propyl)-1,3-dihydro isobenzo furan-5-carbonitrile hydrochloride
Synonyms EsCitalopram EP Impurity D/ Citalopram Related Compound D/ N-Desmethyl Citalopram
Description Citalopram EP Impurity D (HCl salt) (CAS No: 97743-99-2) or Citalopram Related Compound D/ N-Desmethyl Citalopram is a major metabolite of Citalopram. Citalopram is a selective 5-hydroxytryptamine reuptake inhibitor that has been used primarily in the treatment of major depression. Citalopram had efficacy similar to tricyclic or tetracyclic antidepressants.
References Velez de Mendizabal, Nieves, et al. “A Population PK Model for Citalopram and Its Major Metabolite, N-Desmethyl Citalopram, in Rats.” Journal of Pharmacokinetics and Pharmacodynamics, vol. 42, no. 6, Sept. 2015, pp. 721–33, https://doi.org/10.1007/s10928-015-9448-7. Noble, Stuart, and Paul Benfield. “Citalopram.” CNS Drugs, vol. 8, no. 5, Nov. 1997, pp. 410–31, https://doi.org/10.2165/00023210-199708050-00009.

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