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Citalopram EP Impurity E

Citalopram EP Impurity E

Catalogue No.: VL920001
CAS No.: 64169-46-6

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Name: Citalopram EP Impurity E
Catalogue No. VL920001
CAS No. 64169-46-6
Molecular Formula C21H23ClFNO5
Molecular Weight 423.86
Status In-stock
IUPAC Name 1-(4'-Fluorophenyl)-1-(3-dimethylaminopropyl)-5-chlorophthalane oxalate ;
Synonyms Citalopran Chloro Analog / Citalopran Related Compound G / 5-Chlorodescyano Citalopram Oxalate
Appearance White Powder
Description Citalopram EP Impurity E (CAS No: 64169-46-6) or Citalopram USP Related Compound G / Citalopram 5-Chloro Analog HBr is a bromine analog of Citalopram. Citalopram is a new bicyclic phthalane derivative and is an extremely potent inhibitor of neuronal serotonin (5-HT) uptake. Citalopram has no antagonistic activity towards 5-HT, histamine, GABA, acetylcholine, and morphine receptors.
References Karramkam, Mylène, et al. “Synthesis of a Fluorine-18-Labelled Derivative of 6-Nitroquipazine, as a Radioligand for the in Vivo Serotonin Transporter Imaging with PET.” Bioorganic & Medicinal Chemistry, vol. 10, no. 8, Aug. 2002, pp. 2611–23, https://doi.org/10.1016/s0968-0896(02)00098-6. ‌Hyttel, John. “Citalopram — Pharmacological Profile of a Specific Serotonin Uptake Inhibitor with Antidepressant Activity.” Progress in Neuro-Psychopharmacology and Biological Psychiatry, vol. 6, no. 3, Jan. 1

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