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Citalopram EP Impurity F

Citalopram EP Impurity F

Catalogue No.: VL920002
CAS No.: 64169-39-7

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Name: Citalopram EP Impurity F
Catalogue No. VL920002
CAS No. 64169-39-7
Molecular Formula C19H21BrFNO
Molecular Weight 378.28
Status In-stock
IUPAC Name 1-(4'-Fluorophenyl)-1-(3-dimethylaminopropyl)-5-bromophthalane
Synonyms Citalopran Bromo Analog / Citalopram Related Compound H / 5-Bromodescyano Citalopram
Appearance Off White Powder
Description Citalopram EP Impurity F (CAS No: 64169-39-7) or 5-Bromodescyano Citalopram is a Bromo analog of Citalopram. Citalopram is a serotonin reuptake inhibitor that has is shown to be highly selective and has a superior tolerability profile to the classical tricyclic antidepressants.
References Topiol, Sid, et al. “X-Ray Structure Based Evaluation of Analogs of Citalopram: Compounds with Increased Affinity and Selectivity Compared with R-Citalopram for the Allosteric Site (S2) on HSERT.” Bioorganic & Medicinal Chemistry Letters, vol. 27, no. 3, Feb. 2017, pp. 470–78, https://doi.org/10.1016/j.bmcl.2016.12.037. ‌Wade, A. G., et al. “The Effect of Citalopram in Panic Disorder.” British Journal of Psychiatry, vol. 170, no. 6, June 1997, pp. 549–53, https://doi.org/10.1192/bjp.170.6.549.

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