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Clarithromycin EP Impurity D

Clarithromycin EP Impurity D

Catalogue No.: VL740002
CAS No.: 101666-68-6

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Name: Clarithromycin EP Impurity D
Catalogue No. VL740002
CAS No. 101666-68-6
Molecular Formula C37H67NO13
Molecular Weight 733.93
Status In-stock
IUPAC Name 3″-N-Demethyl-6-O-methylerythromycin A
Synonyms N-Desmethyl Clarithromycin
Appearance White solid
Description Clarithromycin EP Impurity D (CAS No: 101666-68-6) or N-Desmethyl Clarithromycin is a metabolite of Clarithromycin. Clarithromycin is a macrolide antibacterial and is metabolized by cytochrome P450 and has substantial dispersal into saliva, sputum, lung tissue, alveolar macrophages, neutrophils, nasal mucosa, and middle ear fluid.
References Baumann, Michaela, et al. “Aquatic Toxicity of the Macrolide Antibiotic Clarithromycin and Its Metabolites.” Chemosphere, vol. 120, Feb. 2015, pp. 192–98, https://doi.org/10.1016/j.chemosphere.2014.05.089. Rodvold, Keith A. “Clinical Pharmacokinetics of Clarithromycin.” Clinical Pharmacokinetics, vol. 37, no. 5, 1999, pp. 385–98, https://doi.org/10.2165/00003088-199937050-00003.

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