| Name: | Clarithromycin EP Impurity D |
| Catalogue No. | VL740002 |
| CAS No. | 101666-68-6 |
| Molecular Formula | C37H67NO13 |
| Molecular Weight | 733.93 |
| Status | In-stock |
| IUPAC Name | 3″-N-Demethyl-6-O-methylerythromycin A |
| Synonyms | N-Desmethyl Clarithromycin |
| Appearance | White solid |
| Description | Clarithromycin EP Impurity D (CAS No: 101666-68-6) or N-Desmethyl Clarithromycin is a metabolite of Clarithromycin. Clarithromycin is a macrolide antibacterial and is metabolized by cytochrome P450 and has substantial dispersal into saliva, sputum, lung tissue, alveolar macrophages, neutrophils, nasal mucosa, and middle ear fluid. |
| References | Baumann, Michaela, et al. “Aquatic Toxicity of the Macrolide Antibiotic Clarithromycin and Its Metabolites.” Chemosphere, vol. 120, Feb. 2015, pp. 192–98, https://doi.org/10.1016/j.chemosphere.2014.05.089. Rodvold, Keith A. “Clinical Pharmacokinetics of Clarithromycin.” Clinical Pharmacokinetics, vol. 37, no. 5, 1999, pp. 385–98, https://doi.org/10.2165/00003088-199937050-00003. |
