| Name: | Clarithromycin EP Impurity H |
| Catalogue No. | VL740006 |
| CAS No. | 127140-69-6 |
| Molecular Formula | C38H67NO14 |
| Molecular Weight | 761.94 |
| Status | In-stock |
| IUPAC Name | 3″-N-Demethyl-3′-N-formyl-6-O-methylerythromycin A ; |
| Synonyms | N-Demethyl-N-formyl Clarithromycin / Clarithromycin Impurity HN-Demethyl-N-formyl Clarithromycin / Clarithromycin Impurity H |
| Appearance | White solid |
| Description | Clarithromycin EP Impurity H (CAS No: 127140-69-6) or N-Demethyl-N-formyl-6-O-methylerythromycin is a metabolite of Clarithromycin. Clarithromycin is a semisynthetic macrolide and shows antibiotic activity. Clarithromycin is well absorbed in the body from the GIT and its bioavailability which is about 55%, is reduced due to first-pass metabolism. |
| References | Fraschini, Franco, et al. “Clarithromycin Clinical Pharmacokinetics.” Clinical Pharmacokinetics, vol. 25, no. 3, Sept. 1993, pp. 189–204, https://doi.org/10.2165/00003088-199325030-00003. |
