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Clarithromycin EP Impurity H

Clarithromycin EP Impurity H

Catalogue No.: VL740006
CAS No.: 127140-69-6

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Name: Clarithromycin EP Impurity H
Catalogue No. VL740006
CAS No. 127140-69-6
Molecular Formula C38H67NO14
Molecular Weight 761.94
Status In-stock
IUPAC Name 3″-N-Demethyl-3′-N-formyl-6-O-methylerythromycin A ;
Synonyms N-Demethyl-N-formyl Clarithromycin / Clarithromycin Impurity HN-Demethyl-N-formyl Clarithromycin / Clarithromycin Impurity H
Appearance White solid
Description Clarithromycin EP Impurity H (CAS No: 127140-69-6) or N-Demethyl-N-formyl-6-O-methylerythromycin is a metabolite of Clarithromycin. Clarithromycin is a semisynthetic macrolide and shows antibiotic activity. Clarithromycin is well absorbed in the body from the GIT and its bioavailability which is about 55%, is reduced due to first-pass metabolism.
References Fraschini, Franco, et al. “Clarithromycin Clinical Pharmacokinetics.” Clinical Pharmacokinetics, vol. 25, no. 3, Sept. 1993, pp. 189–204, https://doi.org/10.2165/00003088-199325030-00003.

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