| Name: | Clarithromycin EP Impurity J |
| Catalogue No. | VL740012 |
| CAS No. | 13127-18-9 |
| Molecular Formula | C37H68N2O13 |
| Molecular Weight | 748.94 |
| Status | In-stock |
| IUPAC Name | Erythromycin A (E)-9-oxime |
| Synonyms | Clarithromycin Impurity J / Erythromycin A Oxime/ Roxithromycin EP Impurity C / Erythromycin 9-(E)-oxime |
| Appearance | White solid |
| Description | Clarithromycin EP Impurity J (CAS No: 13127-18-9) or 9-Erythromycin 9-Oxime is adulteration in Roxithromycin. Roxithromycin is an orally taken antibacterial macrolide that is structurally related to erythromycin and is stable in acid. It has antibacterial activity against Chlamydia trachomatis, Staphylococcus aureus, S. epidermidis, Streptococcus pneumoniae, S. pyogenes, Branhamella catarrhalis, Legionella pneumophila, Gardnerella vaginalis, Haemophilus ducreyi, and some anaerobes. |
| References | Wang, Fan, et al. “Characterization of Nineteen Impurities in Roxithromycin by HPLC/TOF and Ion Trap Mass Spectrometry.” Chromatographia, vol. 76, no. 23-24, Sept. 2013, pp. 1683–95, https://doi.org/10.1007/s10337-013-2557-9. Young, Ronald A., et al. “Roxithromycin.” Drugs, vol. 37, no. 1, Jan. 1989, pp. 8–41, https://doi.org/10.2165/00003495-198937010-00002. |
