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Clarithromycin EP Impurity J

Clarithromycin EP Impurity J

Catalogue No.: VL740012
CAS No.: 13127-18-9

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Name: Clarithromycin EP Impurity J
Catalogue No. VL740012
CAS No. 13127-18-9
Molecular Formula C37H68N2O13
Molecular Weight 748.94
Status In-stock
IUPAC Name Erythromycin A (E)-9-oxime
Synonyms Clarithromycin Impurity J / Erythromycin A Oxime/ Roxithromycin EP Impurity C / Erythromycin 9-(E)-oxime
Appearance White solid
Description Clarithromycin EP Impurity J (CAS No: 13127-18-9) or 9-Erythromycin 9-Oxime is adulteration in Roxithromycin. Roxithromycin is an orally taken antibacterial macrolide that is structurally related to erythromycin and is stable in acid. It has antibacterial activity against Chlamydia trachomatis, Staphylococcus aureus, S. epidermidis, Streptococcus pneumoniae, S. pyogenes, Branhamella catarrhalis, Legionella pneumophila, Gardnerella vaginalis, Haemophilus ducreyi, and some anaerobes.
References Wang, Fan, et al. “Characterization of Nineteen Impurities in Roxithromycin by HPLC/TOF and Ion Trap Mass Spectrometry.” Chromatographia, vol. 76, no. 23-24, Sept. 2013, pp. 1683–95, https://doi.org/10.1007/s10337-013-2557-9. Young, Ronald A., et al. “Roxithromycin.” Drugs, vol. 37, no. 1, Jan. 1989, pp. 8–41, https://doi.org/10.2165/00003495-198937010-00002.

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