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Clarithromycin EP Impurity K

Clarithromycin EP Impurity K

Catalogue No.: VL740010
CAS No.: 127157-35-1

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Name: Clarithromycin EP Impurity K
Catalogue No. VL740010
CAS No. 127157-35-1
Molecular Formula C30H51NO8
Molecular Weight 553.73
Status In-stock
IUPAC Name (1S,2R,5R,6S,7S,8R,9R,11Z)-2-Ethyl-6-hydroxy-9-methoxy-1,5,7,9,11,13-hexamethyl-8-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-3,15-dioxabicyclo[10.2.1]pentadeca-11,13-dien-4-one
Synonyms Clarithromycin Impurity K
Appearance White solid
Description Clarithromycin EP Impurity K (CAS No: 127157-35-1) is a chemical alteration of Erythromycin. Erythromycin is a potent activator of gastrointestinal motor functions. In vitro studies have proved that it depicts motilin's activity which is a peptide that stimulates motor activity in humans through smooth muscle receptors.
References MORIMOTO, SHIGEO, et al. “Chemical Modification of Erythromycins. VI. Structure and Antibacterial Activity of Acid Degradation Products of 6-O-Methylerythromycins A.” The Journal of Antibiotics, vol. 43, no. 5, 1990, pp. 570–73, https://doi.org/10.7164/antibiotics.43.570. ‌“Erythromycin Is a Motilin Receptor Agonist | American Journal of Physiology-Gastrointestinal and Liver Physiology.” American Journal of Physiology-Gastrointestinal and Liver Physiology, 2020, journals.physiology.org/doi/abs/1

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