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Clarithromycin EP Impurity L

Clarithromycin EP Impurity L

Catalogue No.: VL740005
CAS No.: 127253-05-8

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Name: Clarithromycin EP Impurity L
Catalogue No. VL740005
CAS No. 127253-05-8
Molecular Formula C38H70N2O13
Molecular Weight 762.97
Status In-stock
IUPAC Name 6-O-Methylerythromycin A (Z)-9-oxime
Synonyms Clarithromycin Impurity L /Clarithromycin A (Z)-9-oxime
Appearance White solid
Description Clarithromycin EP Impurity L (CAS No: 127253-05-8) or Clarithromycin A (Z)-9-oxime is a potent non-ketolide version of Erythromycin. Erythromycin consists of a 14-membered ring to which two sugars are attached. It is widely used for treating upper and lower respiratory tract infections. It depicts its activity by blocking the release of nascent peptides from the bacterial ribosome.
References Li, Xue-Meng, et al. “Synthesis and Structure-Bactericidal Activity Relationships of Non-Ketolides: 9-Oxime Clarithromycin 11,12-Cyclic Carbonate Featured with Three-to Eight-Atom-Length Spacers at 3-OH.” European Journal of Medicinal Chemistry, vol. 171, June 2019, pp. 235–54, https://doi.org/10.1016/j.ejmech.2019.03.037.

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