
Name: | Clarithromycin EP Impurity L |
Catalogue No. | VL740005 |
CAS No. | 127253-05-8 |
Molecular Formula | C38H70N2O13 |
Molecular Weight | 762.97 |
Status | In-stock |
IUPAC Name | 6-O-Methylerythromycin A (Z)-9-oxime |
Synonyms | Clarithromycin Impurity L /Clarithromycin A (Z)-9-oxime |
Appearance | White solid |
Description | Clarithromycin EP Impurity L (CAS No: 127253-05-8) or Clarithromycin A (Z)-9-oxime is a potent non-ketolide version of Erythromycin. Erythromycin consists of a 14-membered ring to which two sugars are attached. It is widely used for treating upper and lower respiratory tract infections. It depicts its activity by blocking the release of nascent peptides from the bacterial ribosome. |
References | Li, Xue-Meng, et al. “Synthesis and Structure-Bactericidal Activity Relationships of Non-Ketolides: 9-Oxime Clarithromycin 11,12-Cyclic Carbonate Featured with Three-to Eight-Atom-Length Spacers at 3-OH.” European Journal of Medicinal Chemistry, vol. 171, June 2019, pp. 235–54, https://doi.org/10.1016/j.ejmech.2019.03.037. |