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Clarithromycin EP Impurity M

Clarithromycin EP Impurity M

Catalogue No.: VL740003
CAS No.: 127182-43-8

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Name: Clarithromycin EP Impurity M
Catalogue No. VL740003
CAS No. 127182-43-8
Molecular Formula C37H68N2O13
Molecular Weight 748.94
Status In-stock
IUPAC Name 3″-N-Demethyl-6-O-methylerythromycin A (E)-9-oxime ;
Synonyms Clarithromycin Impurity M
Appearance Off White Powder
Description Clarithromycin EP Impurity M (CAS No: 127182-43-8) or Clarithromycin Impurity M is adulteration in Roxithromycin. Roxithromycin is a semi-synthetic 14-membered macrolide antibiotic in which the 9-keto group of the erythromycin A is substituted by an ether-oxime chain. . The drug has activity against few Staphylococcus spp., many Streptococcus spp., Moraxella catarrhalis, Mycoplasma pneumoniae, Legionella pneumophila, and Chlamydia trachomatis.
References Wang, Fan, et al. “Characterization of Nineteen Impurities in Roxithromycin by HPLC/TOF and Ion Trap Mass Spectrometry.” Chromatographia, vol. 76, no. 23-24, Sept. 2013, pp. 1683–95, https://doi.org/10.1007/s10337-013-2557-9. Markham, Anthony, and Diana Faulds. “Roxithromycin.” Drugs, vol. 48, no. 2, Aug. 1994, pp. 297–326, https://doi.org/10.2165/00003495-199448020-00011.

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