| Name: | Clarithromycin EP Impurity M |
| Catalogue No. | VL740003 |
| CAS No. | 127182-43-8 |
| Molecular Formula | C37H68N2O13 |
| Molecular Weight | 748.94 |
| Status | In-stock |
| IUPAC Name | 3″-N-Demethyl-6-O-methylerythromycin A (E)-9-oxime ; |
| Synonyms | Clarithromycin Impurity M |
| Appearance | Off White Powder |
| Description | Clarithromycin EP Impurity M (CAS No: 127182-43-8) or Clarithromycin Impurity M is adulteration in Roxithromycin. Roxithromycin is a semi-synthetic 14-membered macrolide antibiotic in which the 9-keto group of the erythromycin A is substituted by an ether-oxime chain. . The drug has activity against few Staphylococcus spp., many Streptococcus spp., Moraxella catarrhalis, Mycoplasma pneumoniae, Legionella pneumophila, and Chlamydia trachomatis. |
| References | Wang, Fan, et al. “Characterization of Nineteen Impurities in Roxithromycin by HPLC/TOF and Ion Trap Mass Spectrometry.” Chromatographia, vol. 76, no. 23-24, Sept. 2013, pp. 1683–95, https://doi.org/10.1007/s10337-013-2557-9. Markham, Anthony, and Diana Faulds. “Roxithromycin.” Drugs, vol. 48, no. 2, Aug. 1994, pp. 297–326, https://doi.org/10.2165/00003495-199448020-00011. |
