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Clarithromycin EP Impurity O

Clarithromycin EP Impurity O

Catalogue No.: VL740015
CAS No.: 127252-80-6

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Name: Clarithromycin EP Impurity O
Catalogue No. VL740015
CAS No. 127252-80-6
Molecular Formula C39H72N2O13
Molecular Weight 776.99
Status In-stock
IUPAC Name 6-O-Methylerythromycin A (Z)-9-(O-methyloxime)
Synonyms Clarithromycin Impurity O
Appearance White solid
Description Clarithromycin EP Impurity O (CAS No: 127252-80-6) or 6-O-Methylerythromycin A (Z)-9-(O-methyloxime) is a chemical modification of erythromycin. Erythromycin is a macrolide that functions by blocking the translocation reaction at the time of protein synthesis. Erythromycin, except under alkaline conditions, is inactive against the Enterobacteriaceae and Pseudomonas aeruginosa.
References WATANABE, YOSHIAKI, et al. “Chemical Modification of Erythromycins. IX. Selective Methylation at the C-6 Hydroxyl Group of Erythromycin a Oxime Derivatives and Preparation of Clarithromycin.” The Journal of Antibiotics, vol. 46, no. 4, 1993, pp. 647–60, https://doi.org/10.7164/antibiotics.46.647. WASHINGTON, JOHN A., and WALTER R. WILSON. “Erythromycin: A Microbial and Clinical Perspective after 30 Years of Clinical Use (First of Two Parts).” Mayo Clinic Proceedings, vol. 60, no. 3, Mar. 1985, p

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