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Clindamycin BP Impurity C

Clindamycin BP Impurity C

Catalogue No.: VE006945
CAS No.: 17431-55-9

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Name: Clindamycin BP Impurity C
Catalogue No. VE006945
CAS No. 17431-55-9
Molecular Formula C18H34Cl2N2O5S
Molecular Weight 461.44 g/mol
Status In-Stock
IUPAC Name Methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propylpyrrolidin-2-yl]carbonyl]amino]-1-thio-D-erythro-α-D-galacto-octopyranoside HCl
Description Clindamycin BP Impurity C (CAS No: 17431-55-9) is a Lincomycin derivative and possesses a broad spectrum of antibacterial activities against Streptococcus pneumoniae, Streptococcus pyogenes, Haemophilus influenzae, Moraxella catarrhalis, Mycoplasma pneumoniae, Neisseria gonorrhoeae. It also inhibits the chain elongation of bacterial protein by binding to 23S ribosomal RNA and consequently blocks bacterial protein synthesis.
References Wakiyama, Yoshinari, et al. “Synthesis and Structure–Activity Relationships of Novel Lincomycin Derivatives. Part 2. Synthesis of 7(S)-7-Deoxy-7-(4-Morpholinocarbonylphenylthio)Lincomycin and Its 3-Dimensional Analysis with RRNA.” The Journal of Antibiotics, vol. 69, no. 6, Dec. 2015, pp. 428–39, https://doi.org/10.1038/ja.2015.125.

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