| Name: | Clindamycin BP Impurity C |
| Catalogue No. | VE006945 |
| CAS No. | 17431-55-9 |
| Molecular Formula | C18H34Cl2N2O5S |
| Molecular Weight | 461.44 g/mol |
| Status | In-Stock |
| IUPAC Name | Methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-1-methyl-4-propylpyrrolidin-2-yl]carbonyl]amino]-1-thio-D-erythro-α-D-galacto-octopyranoside HCl |
| Description | Clindamycin BP Impurity C (CAS No: 17431-55-9) is a Lincomycin derivative and possesses a broad spectrum of antibacterial activities against Streptococcus pneumoniae, Streptococcus pyogenes, Haemophilus influenzae, Moraxella catarrhalis, Mycoplasma pneumoniae, Neisseria gonorrhoeae. It also inhibits the chain elongation of bacterial protein by binding to 23S ribosomal RNA and consequently blocks bacterial protein synthesis. |
| References | Wakiyama, Yoshinari, et al. “Synthesis and Structure–Activity Relationships of Novel Lincomycin Derivatives. Part 2. Synthesis of 7(S)-7-Deoxy-7-(4-Morpholinocarbonylphenylthio)Lincomycin and Its 3-Dimensional Analysis with RRNA.” The Journal of Antibiotics, vol. 69, no. 6, Dec. 2015, pp. 428–39, https://doi.org/10.1038/ja.2015.125. |
